A questão elusiva dos íntrons - Parte 1-6

segunda-feira, janeiro 25, 2010

Where Do Introns Come From?

Francesco Catania*, Michael Lynch

Citation: Catania F, Lynch M (2008) Where Do Introns Come From? PLoS Biol 6(11): e283. doi:10.1371/journal.pbio.0060283

Published: November 25, 2008

Copyright: © 2008 Catania and Lynch. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Funding: This work was supported by the National Science Foundation grant MCB-0342431 to ML and MetaCyte funding from the Lilly Foundation to Indiana University.

Abbreviations: CBC, capping-binding complex; CPF, cleavage/polyadenylation factor; NMD, nonsense-mediated decay; ORF, open reading frame; PTC, premature translation termination codon; SF, splicing factor; UTR, untranslated region

* To whom correspondence should be addressed. E-mail: fcatania@indiana.edu

Francesco Catania and Michael Lynch are at the Department of Biology, Indiana University, Bloomington, Indiana, United States of America.

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